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MAPK15 — TWIST1

Text-mined interactions from Literome

Smit et al., Mol Cell Biol 2009 (Neoplasm Metastasis) : This required TrkB kinase activity, a functional mitogen activated protein kinase pathway, suppression of E-cadherin, and induction of Twist , a transcription factor contributing to EMT and metastasis
Hong et al., Cancer Res 2011 (Breast Neoplasms...) : Furthermore, activation of mitogen activated protein kinases ( MAPK ) by an active Ras protein or TGF-ß treatment significantly increases Ser 68 phosphorylation and Twist1 protein levels without altering Twist1 mRNA expression, whereas blocking of MAPK activities by either specific inhibitors or dominant negative inhibitory mutants effectively reduces the levels of both induced and uninduced Ser 68 phosphorylation and Twist protein