Gherzi et al., PLoS Biol 2006
:
AKT phosphorylates the mRNA decay promoting factor KSRP at a unique serine residue, induces its association with the multifunctional protein 14-3-3 , and prevents KSRP interaction with the exoribonucleolytic complex exosome
Shukla et al., Int J Oncol 2009
(Disease Progression...) :
In prostate cancer cells, Akt activation causes increased accumulation of FOXO3A and its binding chaperone protein 14-3-3 in the cytosol