◀ Back to APOB

APOB — VCAM1

Text-mined interactions from Literome

Cominacini et al., Cell adhesion and communication 1999 : Oxidized LDL not only caused a dose dependent increase of ICAM-1, VCAM-1 and E-selectin ( p < 0.001 ), but also synergically increased their TNF-alpha induced expression ( p < 0.001 )
Colomé et al., Atherosclerosis 2000 (Arteriosclerosis) : LDL did not induce the expression of the intercellular cell adhesion molecule-1 ( ICAM-1 ), vascular cell adhesion molecule-1 ( VCAM-1 ) or E-selectin, but it produced a downregulation of endothelial nitric oxide synthase ( NOS III ) mRNA levels
Cominacini et al., Am J Hypertens 2002 : Although zofenoprilat significantly and dose dependently reduced the expression of vascular cell adhesion molecule-1 ( VCAM-1 ), intercellular cell adhesion molecule-1 ( ICAM-1 ), and E-selectin induced by ox-LDL ( P < .01 ) and TNF-alpha ( P < .01 ) on HUVECs, enalaprilat did not
Rosenson et al., Clin Sci (Lond) 2004 (Hypercholesterolemia) : In contrast with the known effects of oxidized LDL on gene activation of ICAM-1 and VCAM-1 , lag times did not correlate with sICAM-1 and sVCAM-1
Cai et al., Circulation 2004 (Cardiovascular Diseases...) : In contrast to Db-LAGE-LD and native LDL, Db-HAGE-LDL induced significant soluble vascular cell adhesion molecule-1 production ( 2.3-fold ), which was blocked by PD98059, NAC, and DPI
Chen et al., Hypertension 2005 : Compared with untransfected cells, ox-LDL treatment ( 50 microg/mL, 24 hours ) markedly induced the expression of the leukocyte adhesion molecules intercellular adhesion molecule-1 ( ICAM-1 ), and vascular cell adhesion molecule-1 (VCAM)-1 as well as matrix metalloproteinase (MMP)-1 in cells transfected with CMV-LOX-1wt ( P < 0.05 ) but not in cells transfected with CMV-LOX-1 ( 1-261 )
Zhu et al., Zhonghua Xin Xue Guan Bing Za Zhi 2005 : On the contrary, ox-LDL did not affect the expression of VCAM-1 by HUVECs
Miyoshi et al., Atherosclerosis 2006 (Atherosclerosis...) : MM-LDL resulted in dramatic induction of MCP-1, VCAM-1 , and HO-1 mRNAs in the cells from B6 mice but exerted little effect in cells from C3H mice ... B6 cells produced significantly more MCP-1 and VCAM-1 proteins in response to MM-LDL than C3H cells
Verna et al., Arterioscler Thromb Vasc Biol 2006 : Using tail vein injection of LDL into LDLR ( -/- ) mice, we were able to maintain atherogenic LDL blood levels, which induced ICAM-1 and VCAM-1 expression in their aortic endothelial cells after 24 hours ... Elevated LDL blood levels, maintained in vivo, increased the expression of the adhesion molecules ICAM-1 and VCAM-1 in aortic endothelial cells
Lei et al., J Nutr 2008 : These results suggest that the suppression of ox-LDL induced E-selectin and VCAM-1 expression by DADS and DATS and, thus, monocyte adhesion to endothelial cells is likely dependent on the PI3K/PKB or PKA/CREB signaling pathway in an adhesion molecule-specific manner
Cheng et al., Acta Pharmacol Sin 2009 (Atherosclerosis) : DHEA could also reduce ox-LDL induced MCP-1 and VCAM-1 expression in untransfected or transfected VSMCs
Zhang et al., Mediators Inflamm 2013 : Expressions of ICAM-1, PECAM-1, and VCAM-1 as well as the levels of intracellular Ca ( 2+ ) are also markedly increased by ox-LDL in a dose dependent manner
Thorne et al., Atherosclerosis 1996 (Coronary Artery Disease) : Modified LDL also induced a significant 3-fold increase in monocyte adhesion to SMCs, but did not induce VCAM-1 or ICAM-1 expression, nor was this adhesion inhibited by neutralising antibodies to VCAM-1 or ICAM-1
Lin et al., Atherosclerosis 1996 (Arteriosclerosis) : The findings presented here link an atheogenic lipoprotein, LDL, with the induction of an adhesion molecule important in atherogenesis Human LDL induces the vascular cell adhesion molecule-1 ( VCAM-1 ) transcriptionally with an increase in mRNA levels through activation of the VCAM promoter
Cominacini et al., J Hypertens 1997 : The addition of lacidipine to human umbilical vein endothelial cells significantly reduced the expression of ICAM-1, VCAM-1 and E-selectin induced by TNF-alpha alone or with oxidized LDL ( P < 0.001 )