Gene interactions and pathways from curated databases and text-mining

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TCF12 — VDR

Text-mined interactions from Literome

Pálmer et al., Nat Med 2004 (Colonic Neoplasms) : We show that the SNAIL transcription factor represses VDR gene expression in human colon cancer cells and blocks the antitumor action of EB1089, a 1,25 ( OH ) ( 2 ) D ( 3 ) analog, in xenografted mice
Larriba et al., Br J Cancer 2005 (Colonic Neoplasms) : Recent data show that SNAIL transcription factor represses VDR expression, and thus abolishes the antiproliferative and prodifferentiation effects of VDR ligands in cultured cancer cells and their antitumour action in xenografted mice
Seoane et al., Mol Endocrinol 2006 (Adenocarcinoma...) : The vitamin D receptor represses transcription of the pituitary transcription factor Pit-1 gene without involvement of the retinoid X receptor
Rowland et al., J Bone Miner Res 2012 (Obesity...) : In the small intestine, VDR expression is regulated by the CDX-2 transcription factor , which binds a polymorphic site in the VDR gene promoter
Jiang et al., J Steroid Biochem Mol Biol 2013 (Neoplasms, Radiation-Induced...) : In addition, we also showed that 1,25 ( OH ) 2D3/VDR directly regulates transcriptional activity of ß-catenin/TCF signaling using the -catenin reporter TopGlow