Jobin et al., Biochemistry 2003
(Calcium Signaling) :
FRET imaging analysis of individual endothelial cells cotransfected with eNOS-ECFP and calmodulin-EYFP shows that VEGF induces interactions between eNOS and calmodulin wherever both are present in the cell
Osuka et al., Stroke 2004
(Brain Ischemia) :
The vascular endothelial growth factor ( VEGF ) contributes to activation of eNOS by Ca2+/calmodulin and also stimulates the protein kinase Akt, which directly phosphorylates eNOS on Ser1177 and increases enzyme activity