Gene interactions and pathways from curated databases and text-mining

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MAPK14 — VEGFC

Text-mined interactions from Literome

Hsieh et al., J Biomed Sci 2004 (Ascites...) : Pharmacological and genetic inhibition assays revealed that the cytoplasmic signaling molecule, p38 MAPK , and the transcriptional factor, NF-kappa B, are critically involved in the transcriptional activation of the VEGF-C gene by Her-2/NEU
Luangdilok et al., Eur J Cancer 2011 (Carcinoma, Squamous Cell...) : Inhibition of p38 MAPK suppressed EGF induced VEGF-C upregulation in CAL 27 cells, but inhibited EGF induced VEGF-A upregulation in Detroit 562 ... Taken together, our evidence suggests that both endogenous and exogenous EGFR activation induces VEGF-A expression requiring both PI3K and MAPK signalling whereas VEGF-C expression is dependent on MAPK , but not the PI3K or mTOR pathways in SCCHN cell lines
Quentmeier et al., BMC cancer 2012 (Leukemia...) : Western blot analyses were performed to examine the effect of VEGF-C on p42/44 MAPK activation ... Mature VEGF-C induced p42/44 MAPK activation in the KDR- /FLT4 ( + ) cell line OCI-AML1 verifying the model character of this cell line for VEGF-C signal transduction studies