Gene interactions and pathways from curated databases and text-mining

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NOS2 — WNT11

Text-mined interactions from Literome

Rigas et al., Trends Mol Med 2004 (Neoplasms) : Mechanistically, NO-aspirin, the best studied NO-NSAID, has pleiotropic effects on cell signaling ( it inhibits Wnt signaling, induces nitric oxide synthase and NF-kappaB activation and induces cyclooxygenase-2 expression ), and this mechanistic redundancy might be central to its mode of action against cancer
Du et al., Cancer Res 2006 : Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling
Du et al., Cancer Res 2009 (Neoplasms) : Wnt/beta-catenin signaling regulates cytokine induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells
Freise et al., J Nutr Biochem 2013 (Inflammation...) : ( + ) -Episesamin inhibits adipogenesis and exerts anti-inflammatory effects in 3T3-L1 ( pre ) adipocytes by sustained Wnt signaling, down-regulation of PPAR? and induction of iNOS