Gene interactions and pathways from curated databases and text-mining

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IL6 — WNT2

Text-mined interactions from Literome

Gustafson et al., J Biol Chem 2006 (Diabetes Mellitus...) : Remarkably, both IL-6 and TNFalpha maintained and augmented the canonical Wnt signaling associated with low axin and high low density lipoprotein receptor related protein ( LRD ), Dishevelled, and beta-catenin levels
Li et al., Cancer prevention research (Philadelphia, Pa.) 2011 (Neoplasm Invasiveness...) : In this study, we investigated the signal transduction in the AR/TMPRSS2-ERG/Wnt signaling network for studying the aggressive behavior of prostate cancer cells and further assessed the effects of BR-DIM and CDF [ natural agents derived synthetic formulation and analogue of 3,3'-diindolylmethane ( DIM ) and curcumin, respectively, with improved bioavailability ] on the regulation of AR/TMPRSS2-ERG/Wnt signaling