Gene interactions and pathways from curated databases and text-mining
APOE: top 25 interacting genes (chr19:45409038-45412650)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only APOE-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-APOE interactions     Show top Genes on graph    

Less-frequently mentioned interactions with APOE, not among the Top 25
Other genes interacting with APOE. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

A2M ACSM3 ACTG1 ADRA1B AGA AGFG1 AGRN
AGTR1 AHSG AK2 AKT1 AKT2 AKT3 ALDOA
ALYREF AMPD3 ANKH ANKHD1 ANP32B ANXA2 AP1M1
AP2B1 AP4E1 APOC1 APOC2 APOC3 APRT ARCN1
ARFGAP1 ARL2 ARPC4 ASNS ATM ATP5C1 BBC3
C19orf52 CA2 CABLES1 CACNA1I CAMSAP1 CAMSAP2 CAMSAP3
CAMTA1 CAPN6 CAPZA1 CASP1 CASP10 CASP12 CASP14
CASP16 CASP2 CASP3 CASP4 CASP5 CASP6 CASP7
CASP8 CASP9 CCT4 CCT5 CCT6A CD36 CDC37
CDC45 CDCP1 CENPJ CEP162 CEP44 CETP CFAP20
CFB CFD CFH CFL1 CHD4 CHKB CLCA2
CLIP1 CLU CNOT1 CNTF COASY COPA CRB1
CRHBP CRKL CROT CSNK2A1 CST3 CTAGE5 CTSD
CTSH CTSL CYP2C18 CYP2C8 DAB1 DCC DCD
DDB1 DDX18 DERL1 DGKG DHX15 DICER1 DIMT1
DMD DNAH11 DNAH3 DNAH5 DNAH6 DNM1P34 DNM1P46
DNM2 DVL1 DYNC1H1 DYNC2H1 DYNC2LI1 DYNLL2 DYNLRB1
ECSIT EDC4 EEF1E1 EGF EIF3B EIF4A1 EIF4H
ELAVL1 EML4 EML6 ENO1 EPHB2 EPN2 ESD
EXOC6 F2 F7 FAM110C FAM71E2 FARSA FBXL12
FGF1 FLNB FN1 FOS FOXA2 FOXG1 FSCN1
FXYD7 GABARAPL3 GABBR1 GALK1 GART GAS2L1 GAS2L2
GAS8 GCDH GCN1L1 GFAP GIP GJC2 GNB1L
GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 GPI
GSTP1 GTSE1 H1FX HADHA HAUS3 HAUS8 HBZ
HCA90 HEATR1 HIST1H1B HIST1H4A HMGB1 HMGB2 HMGCR
HNRNPF HOOK2 HOOK3 HP HPX HSPE1 HTRA1
IFIT3 IFIT5 IFNG IGBP1 IGDCC4 IGF2R IGHG1
IL10 IL11 IL12A IL12B IL13 IL15 IL16
IL18 IL19 IL1A IL1B IL2 IL20 IL21
IL22 IL24 IL25 IL26 IL27 IL3 IL31
IL32 IL33 IL34 IL37 IL4 IL5 IL6
IL7 IL8 IL9 ILF3 INCENP INO80 INVS
IPO7 IQGAP1 IQGAP2 IQSEC1 ITGA2 ITGA4 ITGB5
ITIH1 JAKMIP1 JARID2 JUN KATNA1 KATNAL1 KCNMA1
KIAA0232 KIAA1551 KIF11 KIF12 KIF13B KIF14 KIF15
KIF17 KIF18A KIF18B KIF19 KIF1C KIF20A KIF20B
KIF21B KIF22 KIF23 KIF24 KIF26A KIF26B KIF27
KIF2B KIF2C KIF3A KIF3B KIF3C KIF4A KIF4B
KIF5A KIF5B KIF5C KIF6 KIFC2 KLK3 KPNB1
KRT1 KRT10 KRT13 KRT14 KRT16 KRT18 KRT2
KRT5 KRT6A KRT6B KRT9 LAT LDB3 LDHA
LDHB LEP LGALS9 LIPC LONP1 LOXL4 LRPAP1
LYPLA1 LYPLA2 MACF1 MACROD1 MAP1A MAP1B MAP1LC3A
MAP1LC3B MAP1LC3B2 MAP1LC3C MAP4 MAP6 MAP6D1 MAP7
MAP7D1 MAP7D2 MAP7D3 MAPK1 MAPK10 MAPK11 MAPK12
MAPK13 MAPK14 MAPK15 MAPK3 MAPK4 MAPK6 MAPK7
MAPK8 MAPK9 MAPRE1 MAPRE3 MAPT MAST1 MCM3
MCM4 MCM6 MDH2 MDN1 MID1IP1 MID2 MIF
MRPL43 MRTO4 MSN MSR1 MTTP MTUS1 MTUS2
MYBBP1A MYH10 MYL4 MYLK3 NAA38 NACA NAT10
NCL NCOA3 NEFM NFKB1 NHP2L1 NICN1 NINL
NLRC4 NOP56 NOS1 NOS3 NPHS1 NPM1 NR2C2
NUDC NUP205 NUSAP1 OBSL1 OR2T6 OR3A2 OR8D2
PALB2 PCDH1 PCED1B PCMT1 PCNT PDCD4 PDCD6
PDE4B PDZRN4 PEG3 PF4V1 PFDN2 PFKL PFN1
PHB PHC3 PHGDH PI3 PKM PLA2G4F PLAG1
PLEKHA6 PMVK PPBP PPIH PPP1CB PPP1CC PPT1
PRAM1 PRDX1 PRDX2 PRDX3 PRDX6 PRKACB PRKACG
PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRMT1 PRNP
PRPF8 PRSS1 PRSS3 PSEN1 PSMA3 PSMA4 PSMA5
PSMA6 PSMA7 PSMB6 PSMC5 PSMC6 PSMD13 PTGES3
PTGS2 PTPN20A QTRTD1 RAB5C RALY RANBP2 RANBP3
RASSF1 RASSF3 RASSF5 RCC2 REEP3 RELA RHEB
RLF RMDN3 RNF32 RP1 RPA1 RPL14 RPL23
RPL27A RPL28 RPL32 RPL36 RPL4 RPL8 RPN1
RPS10 RPS16 RPS23 RPS25 RPS26 RPS8 RYR2
S100A7 S100A8 SACS SCAF1 SCARB1 SCN5A SDC1
SDC2 SDC3 SDC4 SEC61B SERPING1 SETX SF3B3
SF3B6 SGOL2 SH3BP5 SHROOM3 SKA1 SLA2 SLC1A5
SLC25A13 SLC9A8 SMARCA4 SNRPA1 SORBS3 SPAG17 SPAG6
SPAST SPATA31A7 SPI1 SPRY2 SPTBN1 SRI ST13
STIP1 STMN1 STRAP TAT TBCA TBCC TBCE
TCP11L1 TCTE3 TEKT4 TEKT5 TFAM TFRC THRAP3
TIA1 TIAM1 TLN1 TLN2 TLR4 TMCC2 TPPP
TPPP3 TPR TRAPPC11 TRIM28 TRIM54 TRIM55 TRIM63
TSC22D1 TTLL1 TTLL12 TTLL8 TTN TTPAL TTR
TUBA1A TUBA1B TUBA3C TUBA3E TUBA4A TUBA4B TUBA8
TUBAL3 TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A
TUBB4B TUBB6 TUBB8 TUBD1 TUBE1 TUBG1 TUBG2
TUBGCP5 TUFM TXN TYMS TYRO3 UBC VAMP8
VLDLR VPS35 WHAMM YWHAG ZNF232 ZNF292 ZNF558
Data information
Please see the Gene Interactions Track Manual.