Gene interactions and pathways from curated databases and text-mining

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CREM — TNF

Text-mined interactions from Literome

Harzenetter et al., J Immunol 2007 (Endotoxemia) : Ectopically expressed ICER directly repressed the LPS stimulated activity of a synthetic Tnf promoter, as well as TNF-alpha protein production driven by the endogenous promoter
Altmayr et al., J Biol Chem 2010 : Using TLR2 stimulated dendritic cells, we show that inhibition of tumor necrosis factor-alpha production by CGRP is dependent on up-regulation of endogenous ICER
Bodor et al., J Biol Chem 1998 : Moreover, in Jurkat cells, ectopically expressed ICER represses transcription from NFAT mediated, phorbol ester/ionophore activated IL-2, granulocyte-macrophage colony stimulating factor, and tumor necrosis factor-alpha promoters