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CYP2C19 — TNF

Text-mined interactions from Literome

Miyoshi et al., Eur J Pharmacol 2005 : These findings suggest that TNF-alpha plays a key role in endotoxin induced down-regulation of hepatic P-glycoprotein, as well as plays a protective role in the regulation of hepatic CYP3A2 and CYP2C11 against endotoxin induced acute inflammatory response
Elmarakby et al., Hypertension 2006 (Albuminuria...) : Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension ... These data suggest that TNF-alpha contributes to downregulation of Cyp2c23 , blood pressure regulation, and renal injury in angiotensin high-salt hypertension
Elmarakby et al., Hypertension 2007 (Hypertension) : Renal tumor necrosis factor-alpha and intercellular adhesion molecule-1 expression increased, and Cyp2c23 expression decreased in ANG/HS hypertension compared with the HS group, and CCR2b inhibition reduced tumor necrosis factor-alpha and intercellular adhesion molecule-1 and increased Cyp2c23 expression