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GP9 — TNF

Text-mined interactions from Literome

Pukhal'skii et al., Bull Exp Biol Med 2001 (Inflammation) : We studied the effects of alpha1-acid glycoprotein on tumor necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10) production and lymphocyte response to phytohemagglutinin in cultured peripheral blood mononuclear leukocytes from 6 healthy donors
Tabor et al., J Cell Physiol 1992 : Macrophage membrane glycoprotein binding of Griffonia simplicifolia I-B4 induces TNF-alpha production and a tumoricidal response
Belliard et al., J Pharm Sci 2004 : Effect of tumor necrosis factor-alpha and interferon-gamma on intestinal P-glycoprotein expression, activity, and localization in Caco-2 cells
Matsuzaki et al., Clin Diagn Lab Immunol 2004 (MAP Kinase Signaling System) : ( v ) Bikunin is functional in vivo, and this glycoprotein blocks systemic TNF-alpha release in mice challenged with LPS
Miyoshi et al., Eur J Pharmacol 2005 : Role of tumor necrosis factor-alpha in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin ... We investigated the role of tumor necrosis factor-alpha (TNF-alpha) in the down-regulation of hepatic P-glycoprotein and cytochrome P450 ( CYP ) by endotoxin, using TNF-alpha gene-deficient (TNF-alpha-/-) mice ... These results suggest that TNF-alpha plays a pivotal role in the down-regulation of P-glycoprotein by endotoxin ... These findings suggest that TNF-alpha plays a key role in endotoxin induced down-regulation of hepatic P-glycoprotein , as well as plays a protective role in the regulation of hepatic CYP3A2 and CYP2C11 against endotoxin induced acute inflammatory response
Kina et al., Int J Parasitol 2005 : The glycoprotein , plerocercoid-immunosuppressive factor, from crude ES products could suppress the gene expression of TNF-alpha , IL-1beta and NO synthesis in LPS stimulated RAW264.7 macrophages
Bauer et al., Mol Pharmacol 2007 : TNF-alpha signaled through TNF-R1, which in turn caused ET release and action through ETA and ETB receptors, nitric-oxide synthase, protein kinase C and nuclear factor-kappaB (NF-kappaB) and finally increased P-glycoprotein expression and transport activity
Yu et al., Cell Physiol Biochem 2007 : TNF activates P-glycoprotein in cerebral microvascular endothelial cells ... We used microarray, real time RT-PCR, Western blotting, and uptake of vinblastine by RBE4 cerebral endothelial cells to test the effects of tumor necrosis factor alpha (TNF) on the expression and functions of P-glycoprotein ( MDR1 )
Lee et al., Inflamm Res 2009 (Inflammation...) : In addition, ZPDC glycoprotein ( 200 microg/ml ) not only diminished the production of superoxide anion, hydrogen peroxide, and nitric oxide, but also suppressed the expression of pro-inflammatory cytokines ( IL-1 beta, IL-6, and TNF-alpha ) and proteins ( iNOS, COX-2, and MMP-9 ) in LPS- stimulated RAW 264.7 cells
Oh et al., J Cell Biochem 2010 (Anaphylaxis...) : Our results revealed that the CTB glycoprotein in the presence of DEHP inhibits the release of histamine and expression of interleukin (IL)-4, IL-6, and TNF-alpha in RBL-2H3 cells ... The results from these experiments indicated that the CTB glycoprotein inhibits release of histamine and expressions of IL-4, IL-6, and TNF-alpha via down regulations of PKC/MAPK and NF-kappaB on the stage of mast cell degranulation induced by DEHP
Rigor et al., J Cereb Blood Flow Metab 2010 : In this study, we used isolated rat brain capillaries to show that the TNF-alpha induced reduction of P-glycoprotein activity was prevented by a PKCbeta ( I/II ) inhibitor, LY333531, and mimicked by a PKCbeta ( I/II ) activator, 12-deoxyphorbol-13-phenylacetate-20-acetate ( dPPA )
Heemskerk et al., J Biomed Biotechnol 2010 : Regulation of P-glycoprotein in renal proximal tubule epithelial cells by LPS and TNF-alpha
Oh et al., J Appl Toxicol 2010 (Carbon Tetrachloride Poisoning...) : We also found that MIL glycoprotein reduced the activity of COX-2 and expression of TNF-a and IL-1 beta in liver from CCl ( 4 ) -treated mice
Al-Bataineh et al., Biopharm Drug Dispos 2010 (Inflammation) : In this study, the role of TNF-a in the regulation of P-glycoprotein was determined in cultured BME-UV cells, an immortalized bovine mammary epithelial cell line
Dai et al., International journal of molecular sciences 2011 : Interleukin-6 and tumor necrosis factor-a levels in the lipopolysaccharide induced peripheral blood mononuclear cell supernates were significantly reduced by spermine and/or a2-Heremans-Schmid glycoprotein
Cartwright et al., J Cereb Blood Flow Metab 2013 : In brain and spinal cord capillaries isolated from wild-type mice, TNF-a , sphingosine, S1P, the S1PR agonist fingolimod ( FTY720 ), and its active, phosphorylated metabolite, FTY720P, reduced P-glycoprotein transport activity ; these effects were abolished by a specific S1PR1 antagonist
Scuderi et al., Eur J Immunol 1989 : The secretion of tumor necrosis factor (TNF) by human peripheral blood mononuclear cells was suppressed by either whole human plasma alpha-globulins or purified alpha 1-acid-glycoprotein , alpha 1-antitrypsin and alpha 2-macroglobulin in a concentration dependent manner
Andreana et al., J Infect Dis 1994 : Furthermore, recombinant TNF alpha had no effect on the induction of P glycoprotein expression in U1 cells
Herbert et al., FEBS Lett 1993 : Endotoxin ( LPS ), interleukin-1 beta (IL-1) and tumor necrosis factor-alpha (TNF) increased the expression of tissue factor, a membrane anchored glycoprotein that initiates blood coagulation on the surface of cultured bovine aortic endothelial cells ( ABAE ) and human monocytes
Ehrenreich et al., J Immunol 1993 (AIDS Dementia Complex...) : We found that glycoprotein 120, similar to LPS, stimulates the secretion of endothelin-1, as well as TNF-alpha , from macrophages in a concentration dependent manner
Turk et al., Proc Natl Acad Sci U S A 1996 : Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production
Su et al., Immunopharmacology 1996 : Effects of alpha 1-acid glycoprotein on tissue factor expression and tumor necrosis factor secretion in human monocytes ... We investigated the effect of alpha 1-acid glycoprotein ( alpha 1-AGP ), an acute phase protein, on the induction of the expression of TF and the secretion of TNF alpha in human monocytes in vitro
Andrejko et al., Crit Care Med 1996 (Sepsis) : To test the hypothesis that after cecal ligation and puncture in the rat, there is increased expression of the tumor necrosis factor (TNF)/interleukin-1 dependent , acute-phase reactant alpha 1-acid glycoprotein in the liver, and that this change correlates temporally with increased abundance of TNF-alpha in the hepatic parenchyma but not with circulating concentrations of TNF-alpha