Gene interactions and pathways from curated databases and text-mining

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PDCD7 — TNF

Text-mined interactions from Literome

Pryhuber et al., Am J Respir Cell Mol Biol 2000 (Pneumonia) : Tumor necrosis factor (TNF) receptor ( TNFR ) -associated factors 1 and 2 ( TRAF1 and TRAF2 ) and inhibitor of apoptosis proteins cIAP1 ( MIHB ) and cIAP2 ( MIHC ) were recently identified as proteins that associate with the TNF-alpha receptors TNFRI ( p55 ) and TNFRII ( p75 ) and inhibit TNF-alpha induced programmed cell death or apoptosis
Arrigo et al., Pathol Biol (Paris) 2000 (Neoplasms) : These proteins are also known to interfere with programmed cell death induced by TNF alpha and Fas ligand
Robichaud et al., AIDS Res Hum Retroviruses 2000 : Since ceramide is an important regulatory molecule of programmed cell death induced by TNF-alpha , we examined whether nef could alter TNF-alpha induced apoptosis in the U251MG human astrocytoma cell line
Ivanov et al., Oncogene 2001 (Melanoma) : Our finding identifies p38, TNFalpha and NF-kappaB among key players that efficiently sensitizes melanoma cells to UV-, ribotoxic ( anisomycin ) and radiomimetic chemicals induced programmed cell death in response to aberrant TRAF2 signaling
Tang et al., Nature 2001 : The proinflammatory cytokine tumour necrosis factor-alpha (TNF-alpha) regulates immune responses, inflammation and programmed cell death ( apoptosis )
Huber et al., Digestion 2002 : The aim of our current study was to identify the effect of TNF-alpha on programmed cell death
Cusson et al., J Exp Med 2002 : Fas and the tumor necrosis factor receptor (TNFR)1 regulate the programmed cell death of lymphocytes
Tang et al., Mol Cell Biol 2002 (MAP Kinase Signaling System) : The proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) regulates immune responses, inflammation, and programmed cell death ( apoptosis )
Bezzi et al., J Biol Chem 2003 : Zoledronate sensitizes endothelial cells to tumor necrosis factor induced programmed cell death : evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B/Akt ... Taken together these data demonstrate that zoledronate sensitizes endothelial cells to TNF induced , caspase independent programmed cell death and point to the FAK-PKB/Akt pathway as a novel zoledronate target
Dinarello et al., Clin Exp Rheumatol 2002 (Autoimmune Diseases) : IL-1 is distinct from tumor necrosis factor (TNF) ; IL-1 and TNFalpha share several biological properties but the salient difference is that TNF receptor signaling induces programmed cell death whereas IL-1 receptor signaling does not
Weitsman et al., J Steroid Biochem Mol Biol 2004 (Breast Neoplasms) : Activation of p38 MAP kinase was shown to have both pro- and anti-apoptotic actions in TNF-alpha induced programmed cell death depending on cell context
Lecour et al., Cardiovasc Res 2005 (Myocardial Ischemia...) : Tumor Necrosis Factor alpha (TNF alpha) induces programmed cell death and contributes to cardiac ischemia/reperfusion injury
Pajak et al., J Physiol Pharmacol 2005 (Colorectal Neoplasms) : Apparently, cycloheximide sensitized cells to TNF-alpha induced programmed cell death
Lange et al., Biochem Biophys Res Commun 2005 : The apoptosis inhibitory domain of FE65-like protein 1 regulates both apoptotic and caspase independent programmed cell death mediated by tumor necrosis factor
Varfolomeev et al., J Biol Chem 2005 : Apo2 ligand/tumor necrosis factor (TNF) related apoptosis inducing ligand ( Apo2L/TRAIL ) mainly activates programmed cell death through caspases
Zhang et al., Chin Med J (Engl) 2007 (Carcinoma, Adenoid Cystic...) : A20, also known as tumor necrosis factor alpha induced protein 3 ( TNFaip3 ), is a cytoplasmic zinc finger protein that inhibits nuclear factor kappa-B (NF-kappaB) activity and prevents tumor necrosis factor (TNF) mediated programmed cell death
Wei et al., BMC biotechnology 2008 : A20 is a cytoplasmic zinc finger protein that inhibits nuclear factor kappa-B activity and tumor necrosis factor (TNF) mediated programmed cell death
Oshima et al., Nature 2009 : ABIN-1 deficient cells are hypersensitive to tumour necrosis factor (TNF) induced programmed cell death , and TNF deficiency rescues ABIN-1 deficient embryos
Seixas et al., Proc Natl Acad Sci U S A 2009 (Liver Failure...) : Expression of HO-1 suppresses the pro-oxidant effects of free heme, preventing it from sensitizing hepatocytes to undergo TNF mediated programmed cell death by apoptosis
Mangan et al., J Immunol 1991 : Lipopolysaccharide, tumor necrosis factor-alpha , and IL-1 beta prevent programmed cell death ( apoptosis ) in human peripheral blood monocytes
Tavares et al., Immunity 2010 : A20 is a ubiquitin modifying enzyme that restricts NF-kappaB signals and protects cells against tumor necrosis factor (TNF) induced programmed cell death
Guan et al., Biomaterials 2010 : It is thus suggested that the co-immobilized TNF-a plus IFN-? promotes the activation of some unknown key markers in response to IFN-?, and the binding of the co-immobilized TNF-a plus IFN-? with some other TNF-a receptors results in enhanced programmed cell death in HeLa cells
Eissner et al., Blood 1995 : Critical involvement of transmembrane tumor necrosis factor-alpha in endothelial programmed cell death mediated by ionizing radiation and bacterial endotoxin
Tabibzadeh et al., Hum Reprod 1995 : It has been suggested that tumour necrosis factor (TNF) alpha secreted during the secretory/menstrual phases plays a role in induction of programmed cell death in these cells
Selleri et al., J Cell Physiol 1995 : Interferon-gamma and tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and induce programmed cell death
Ayala et al., Shock 1995 (Sepsis) : The induction of accelerated thymic programmed cell death during polymicrobial sepsis : control by corticosteroids but not tumor necrosis factor
Baier-Bitterlich et al., FEBS Lett 1995 : Effect of neopterin and 7,8-dihydroneopterin on tumor necrosis factor-alpha induced programmed cell death
Gotlieb et al., Am J Obstet Gynecol 1994 (Ovarian Neoplasms) : Induction of programmed cell death ( apoptosis ) by tumor necrosis factor-alpha was quantitated by means of a deoxyribonucleic acid fragmentation assay
Briskin et al., Arch Otolaryngol Head Neck Surg 1996 (Carcinoma, Squamous Cell...) : Specifically, to find out whether TNF-alpha induces apoptotic ( programmed ) cell death
Cuvillier et al., Nature 1996 : Ceramide is an important regulatory participant of programmed cell death ( apoptosis ) induced by tumour-necrosis factor (TNF)-alpha and Fas ligand, members of the TNF superfamily
Deiss et al., EMBO J 1996 : Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha
Sytwu et al., Immunity 1996 (Lymphoproliferative Disorders) : The roles of Fas/APO-1 ( CD95 ) and TNF in antigen induced programmed cell death in T cell receptor transgenic mice
Watson et al., Shock 1996 (Inflammation) : Bacterial ingestion, tumor necrosis factor-alpha , and heat induce programmed cell death in activated neutrophils ... The results demonstrate, for the first time, that the mechanisms by which LPS delays PMN apoptosis are overridden by the mechanisms by which TNF-alpha , E. coli ingestion, and heat shock induce programmed cell death
Shu et al., Proc Natl Acad Sci U S A 1996 : The association of TRADD, a 34-kDa cytoplasmic protein containing a C-terminal death domain, with aggregated TNF receptor 1 (TNF-R1) through their respective death domains leads to NF-kappa B activation and programmed cell death
Schubert et al., Ann N Y Acad Sci 1997 : Adenosine agonists also depressed the release of the potentially toxic cytokine TNF alpha and induced programmed cell death in immunologically activated microglial cells
Tollefson et al., Nature 1998 : In adenovirus infected cells, programmed cell death ( apoptosis ) induced by the cytokine tumour necrosis factor (TNF) is inhibited by several adenovirus encoded proteins
Wuttke et al., J Reprod Fertil Suppl 1997 : Furthermore, TNF alpha stimulates programmed cell death ( apoptosis ) in luteal cells kept under culture conditions
Wang et al., Nat Genet 1998 (Leukemia, Promyelocytic, Acute) : We also found that Pml is essential for induction of programmed cell death by Fas, tumour necrosis factor alpha (TNF) , ceramide and type I and II interferons ( IFNs )