Gene interactions and pathways from curated databases and text-mining

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ABCC1 — PAK2

Text-mined interactions from Literome

Ren et al., Biochem Biophys Res Commun 2000 : However, PAK-104P , a pyridine analog that reverses MDR associated with P-gp and MRP1, inhibited the transporting activity of MRP1 stronger than that of YCF1
Sumizawa et al., Mol Pharmacol 1997 : These findings demonstrate that PAK-104P can completely reverse the resistance to VCR in both P-Gp- and MRP mediated multidrug-resistant cells and that PAK-104P directly interacts with MRP and inhibits the transporting activity of MRP
Chen et al., Biochem Biophys Res Commun 1997 : These findings suggest that MRP transports antimony conjugated with GSH ATP-dependently outside the cells and PAK-104P inhibits the transporting activity of MRP