Gene interactions and pathways from curated databases and text-mining

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ABCG2 — IL4

Text-mined interactions from Literome

Staege et al., Immunogenetics 2001 (Listeriosis) : In addition, we report several novel effects of deactivators and infection on the expression of known genes : ( 1 ) IL-4 caused pronounced upregulation of ABCG2 , coding for an ATP binding cassette transporter highly expressed in the placenta, which mediates multidrug resistance of cancer cells, but is otherwise of unknown function ; ( 2 ) both DEX and IL-4 downregulated osteopontin, an important factor of host resistance against intracellular infections ; ( 3 ) inhibition of the CC-chemokine I-309 mRNA expression by all three deactivators in the presence of Listeria infection, and ( 4 ) upregulation by Listeria infection of the interferon stimulated gene ISG20 of unknown function, whose product localizes with nuclear dots/PML bodies
Zhang et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2007 (Adenocarcinoma...) : [ Effect of IL-4 on ABCG2 expression in human lung adenocarcinoma cell lines ] ... To investigate the effect of IL-4 on the expression of ABCG2 in lung adencarcinoma cell lines ... IL-4 does not regulate ABCG2 expression in human lung adencarcinoma cell lines