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ABL1 — MUC1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ABL1 — MUC1 (physical association, affinity chromatography technology) Raina et al., EMBO J 2006*
• IRef Biogrid Interaction: ABL1 — MUC1 (direct interaction, enzymatic study) Raina et al., EMBO J 2006*
• IRef Hprd Interaction: ABL1 — MUC1 (in vivo) Raina et al., EMBO J 2006*
• IRef Intact Interaction: MUC1 — ABL1 (physical association, anti bait coimmunoprecipitation) Raina et al., EMBO J 2006*
• IRef Intact Interaction: MUC1 — ABL1 (direct interaction, pull down) Raina et al., EMBO J 2006*
• IRef Intact Interaction: MUC1 — ABL1 (physical association, anti tag coimmunoprecipitation) Raina et al., EMBO J 2006*
• IRef Intact Interaction: MUC1 — ABL1 (colocalization, imaging technique) Raina et al., EMBO J 2006*
• IRef Intact Interaction: MUC1 — ABL1 (phosphorylation reaction, protein kinase assay) Raina et al., EMBO J 2006*

Text-mined interactions from Literome

Raina et al., EMBO J 2006 : We also show that expression of MUC1 with a mutation at Tyr-60 ( i ) disrupts the interaction between MUC1 and c-Abl, ( ii ) relieves the MUC1 induced block of c-Abl phosphorylation on Thr-735 and binding to 14-3-3, and ( iii ) attenuates the MUC1 antiapoptotic function
Kawano et al., Cancer Res 2007 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive...) : These findings indicate that MUC1 stabilizes Bcr-Abl and contributes to the pathogenesis of CML cells by promoting self renewal and inhibiting differentiation and apoptosis