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ADCY1 — PTHLH
Text-mined interactions from Literome
Hömme et al., Endocrinology 2003
(Osteosarcoma) :
The
PTH/PTHrP receptor
stimulates both
adenylate cyclase- and phospholipase C-dependent signaling pathways via different G proteins
Trizna et al., Pharmacology 1991
:
In proximal convoluted tubules PTH and
PTHrP stimulated
adenylate cyclase to the same extent and with similar potencies
Azarani et al., J Biol Chem 1995
:
Human PTH- ( 1-34 ) and
PTHRP- ( 1-34 )
stimulated adenylate cyclase and PKC activity, whereas the PTH analogues, PTH- ( 3-34 ), PTH- ( 28-42 ), and PTH- ( 28-48 ), selectively enhanced only PKC activity
Suda et al., J Cell Physiol 1996
(Osteosarcoma) :
Examination of the populations obtained from newborn rat calvariae by sequential collagenase digestion revealed that the early digests exhibited low ALP activity, low expression of PTH/PTHrP receptor mRNA, and no
adenylate cyclase response to
PTHrP ( 1-34 )
Azarani et al., J Biol Chem 1996
:
Both PTH- ( 1-34 ) and
PTHRP- ( 1-34 )
stimulated adenylate cyclase and PKC activities in these cells, whereas PTH- ( 3-34 ), PTH- ( 28-42 ), and PTH- ( 28-48 ) selectively enhanced only PKC activity