Gene interactions and pathways from curated databases and text-mining

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AKT1 — CDKN2A

Text-mined interactions from Literome

Hashimoto et al., Cancer Res 2004 : In addition, caffeine did not affect p16INK4 or p27Kip1 protein levels, but inhibited the phosphorylation of protein kinase B ( Akt ) and glycogen synthase kinase 3beta
Katayama et al., Oncogene 2008 : Inhibition of Akt signaling by PI3K inhibitors, a PDK1 inhibitor, or dominant negative Akt transfection increased expression of p15(INK4b) and p19(INK4d) but not p16(INK4a) and p18(INK4c)