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ANG — IL6

Text-mined interactions from Literome

Schieffer et al., Circ Res 2000 : Ang II activates the JAK/STAT cascade via its type 1 ( AT(1) ) receptor and induces synthesis and release of IL-6
Sano et al., Circ Res 2001 : We recently reported that angiotensin II (Ang II) induced IL-6 mRNA expression in cardiac fibroblasts, which played an important role in Ang II-induced cardiac hypertrophy in paracrine fashion
Niimi et al., Jpn J Pharmacol 2002 : The present study was designed to clarify the role of angiotensin II (Ang II) in modulating renal tumor necrosis factor (TNF)-alpha and interleukin-6 (IL-6) production and to investigate the effect of one dose of Ang II inhibitor on cytokines production following lipopolysaccharide (LPS) to cause endotoxemia
Shcheglovitova et al., Bull Exp Biol Med 2003 : Angiogenin isolated from cow milk induces the production of cytokines IL-1beta, IL-6 , and TNF-alpha in human leukocytes ; the level of production of each cytokine depends on the concentration of the preparation, and the dynamics of production depends on the time from the beginning of induction
Luchtefeld et al., Biochem Biophys Res Commun 2003 : Angiotensin II (ANG II) induced interleukin (IL)-6 synthesis requires NAD ( P ) H-oxidase derived superoxide anions
Chen et al., Am J Physiol Heart Circ Physiol 2004 (Myocarditis...) : HS treatment blocked ANG II induced expression of IL-6 and ICAM-1 in the heart
Schrader et al., Arterioscler Thromb Vasc Biol 2007 (Hypertrophy) : These data demonstrate that IL-6 is essential for Ang II-induced increases in superoxide, endothelial dysfunction, and vascular hypertrophy
Satou et al., American journal of physiology. Renal physiology 2008 : Augmented intrarenal ANG II stimulates IL-6 , which contributes to renal injury
Kandalam et al., Regul Pept 2010 : In addition, Ang II stimulated IL-6 secretion and astrocyte growth through the JAK2 pathway in brainstem astrocytes
Gao et al., Ann Rheum Dis 2013 (Arthritis, Psoriatic...) : Finally, DAPT significantly decreased VEGF/Ang2 induced IL-6 , IL-8, MMP2 and 9 expressions in RA synovial explants
Ju et al., Arterioscler Thromb Vasc Biol 2013 (Aneurysm, Dissecting...) : Dysregulated angiotensin II (Ang II) signaling induces local vascular interleukin-6 (IL-6) secretion, producing leukocyte infiltration and life threatening aortic dissections