Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — MAP2K3

Text-mined interactions from Literome

Kang et al., J Mol Endocrinol 2006 (MAP Kinase Signaling System) : Furthermore, stimulation of the cells with Ang-II increased both phosphorylation of p38 MAPK and MAP kinase kinase 3/6 ( MKK3/6 )
Shimizu et al., FASEB J 2008 (Osteoporosis) : Of importance, Ang II significantly induced the expression of receptor activator of NF-kappaB ligand ( RANKL ) in osteoblasts, leading to the activation of osteoclasts, whereas these effects were completely blocked by an Ang II type 1 receptor blockade ( olmesartan ) and mitogen activated protein kinase kinase inhibitors