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AKT2 — APC

Text-mined interactions from Literome

Buttrick et al., J Cell Biol 2008 : We show that Akt is enriched at the embryonic cortex and is required for phosphorylation of the glycogen synthase kinase-3beta homologue Zeste-white 3 kinase ( Zw3 ) and for the cortical localizations of the adenomatosis polyposis coli (APC) related protein APC2/E-APC and the MT + Tip protein EB1
Yang et al., Proc Natl Acad Sci U S A 2009 : Here we used human monocytic-like U937 cells to evaluate apolipoprotein E receptor 2 (ApoER2) dependent signaling by APC and found that APC initiated rapid phosphorylation of Tyr-220 in the adaptor protein disabled-1 (Dab1) and of Ser-473 in Akt
Gramling et al., Exp Cell Res 2010 (Breast Neoplasms...) : Intracellularly, APC activates ERK, Akt , and NFkappaB, but not the JNK pathway to promote MDA-MB-231 cell motility
Matsumoto et al., J Bone Miner Res 2013 (Bone Resorption) : Forced Akt activation increased the binding of the microtubule associated protein adenomatous polyposis coli (APC) , the APC binding protein end binding protein 1 (EB1) and dynactin, a dynein activator complex, with microtubules
Guo et al., J Neurosci 2013 : 3K3A-APC activated Akt , a downstream target of S1PR1, which was inhibited by S1PR1, PAR1, and PAR3 silencing