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APC — CDK1

Pathways - manually collected, often from reviews:

• WikiPathways Cell Cycle: CDH1/APC → CDK1 (activation)

Text-mined interactions from Literome

Listovsky et al., Exp Cell Res 2000 : Cdk1 is essential for mammalian cyclosome/APC regulation
Rappleye et al., Dev Cell 2002 : The APC is also required for tight cortical association and posterior movement of the paternal pronucleus and its associated centrosome
Bolte et al., Proc Natl Acad Sci U S A 2002 : IME2 expression resulted in the phosphorylation of Cdh1 in G1 cells, indicating that Ime2 and Cdk1 regulate APC ( Cdh1 ) in a similar manner
Margottin-Goguet et al., Dev Cell 2003 : To ensure that cyclin B/Cdc2 does not prematurely activate the APC in early mitosis, there must be a mechanism delaying APC activation
Kraft et al., EMBO J 2003 : These observations imply that APC activation is initiated by Cdk1 already in the nuclei of late prophase cells
Reis et al., Nat Cell Biol 2007 : The switch from APC ( cdh1 ) to APC ( cdc20 ) activity was controlled by increasing CDK1 and cdh1 loss