Gene interactions and pathways from curated databases and text-mining

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AKT3 — APOA1

Text-mined interactions from Literome

Rämet et al., J Am Coll Cardiol 2003 (Arteriosclerosis) : Both HDL and apoA-I activated mitogen activated protein-kinase and phosphatidylinositol 3-kinase (PI3K) Akt-pathways in human arterial endothelial cells, and inhibition of either of these pathways by specific pharmacologic inhibitors abolished the effect of HDL on eNOS
Wang et al., Lipids in health and disease 2012 (Obesity) : HDL and apoA-I could activate PI3K-Akt-mTORC1 signaling which negatively regulates autophagy