Gene interactions and pathways from curated databases and text-mining

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BCR — PPP2CA

Text-mined interactions from Literome

Neviani et al., Cancer Cell 2005 (Blast Crisis...) : In imatinib-sensitive and -resistant ( T315I included ) BCR/ABL+ cell lines and CML-BC progenitors, molecular and/or pharmacological activation of PP2A promotes dephosphorylation of key regulators of cell proliferation and survival, suppresses BCR/ABL activity, and induces BCR/ABL degradation
Hu et al., PloS one 2009 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : While exerting suppressive effects on BCR-ABL , E2F1, and beta-catenin, IM/BOR and IM/PSI inhibited proteasomal degradation of protein phosphatase 2A (PP2A) , leading to a re-activation of this important negative regulator of BCR-ABL