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BMP1 — IL6

Text-mined interactions from Literome

Namba et al., Connect Tissue Res 2007 : We examined the effect of IL-6 and sIL-6Ralpha on cell growth, alkaline phosphatase ( ALPase ) activity, and the expression of Sox-9, type II collagen, aggrecan core, link protein, BMP-7 , and BMP receptors in human chondrocytes ... The expression of Sox-9 and aggrecan core did not change in the presence or absence of IL-6 and sIL-6Ralpha, whereas the expression of type II collagen, link protein, BMP-7 , and BMP receptors increased in the presence of both IL-6 and sIL-6Ralpha ... These results suggest that IL-6 and sIL-6Ralpha suppress the differentiation of chondrocytes and induce the repair of arthrodial cartilage through an increase in the expression of cartilage matrix proteins, BMP-7 , and BMP receptors in the cells
Yu et al., Nat Chem Biol 2008 : In vitro, dorsomorphin inhibited BMP- , hemojuvelin- and interleukin 6-stimulated expression of the systemic iron regulator hepcidin, which suggests that BMP receptors regulate hepcidin induction by all of these stimuli
Ciuclan et al., Am J Respir Crit Care Med 2011 (Acute Disease...) : Molecular analysis showed a dysregulated transforming growth factor-ß/bone morphogenetic protein/Smad axis in SU5416- and/or hypoxia treated mice as well as augmented induction of IL-6 and Hif-1a levels
Kim et al., Food Chem Toxicol 2012 (MAP Kinase Signaling System) : PCP increased the production of nitric oxide ( NO ) and the gene expression of IL-1ß, IL-6 , and TNF-a in RAW 264.7 cells