Gene interactions and pathways from curated databases and text-mining

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C1QA — IL1A

Text-mined interactions from Literome

Fraser et al., J Neurochem 2010 (Blister) : Microglia added to C1q coated wells or fed apoptotic neurons or neuronal blebs coated with C1q suppressed the lipopolysaccharide induced production of proinflammatory cytokines interleukin (IL)-1alpha , IL-1beta, IL-6 and TNF-alpha, while the presence of C1q enhanced levels of the chemokine MCP-1/CCL2
Habicht et al., J Immunol 1987 : C1q inhibits the expression of B lymphoblastoid cell line interleukin 1 (IL 1) ... Similar results were obtained when Daudi and Wil2WT cells were used, whereas Molt4, which is a T cell lymphoblastoid cell line, neither produced `` IL 1-like '' activity nor was affected by C1q ... In addition, the effect of C1q on IL 1 activity was abrogated either when the C1q was heat inactivated ( 56 degrees C, 60 min ) or when the C1q was incubated with the cells in the presence of F ( ab ' ) 2 anti-C1q