◀ Back to IL1A
C1QA — IL1A
Text-mined interactions from Literome
Fraser et al., J Neurochem 2010
(Blister) :
Microglia added to C1q coated wells or fed apoptotic neurons or neuronal blebs coated with C1q suppressed the lipopolysaccharide induced production of proinflammatory cytokines
interleukin (IL)-1alpha , IL-1beta, IL-6 and TNF-alpha, while the presence of
C1q enhanced levels of the chemokine MCP-1/CCL2
Habicht et al., J Immunol 1987
:
C1q inhibits the expression of B lymphoblastoid cell line
interleukin 1 (IL 1) ... Similar results were obtained when Daudi and Wil2WT cells were used, whereas Molt4, which is a T cell lymphoblastoid cell line, neither produced ``
IL 1-like '' activity nor was
affected by
C1q ... In addition, the
effect of
C1q on
IL 1 activity was abrogated either when the C1q was heat inactivated ( 56 degrees C, 60 min ) or when the C1q was incubated with the cells in the presence of F ( ab ' ) 2 anti-C1q