Gene interactions and pathways from curated databases and text-mining

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CALM2 — GRK4

Text-mined interactions from Literome

Freeman et al., FEBS Lett 2000 : In addition, calcium bound calmodulin and phosphatidylinositol 4,5-bisphosphate ( PIP2 ), two regulators of GRK activity, coordinate with alpha-actinin to modulate substrate specificity of the GRKs
Lao et al., Clin Exp Hypertens 2002 (Hypertension) : Because calmodulin kinase ( CaMK ) can regulate GRK activity, CaMK activity in renal cortical membranes of WKHA and WKHT were studied
Monovich et al., FEBS Lett 2010 : Several kinases have been shown to phosphorylate class IIa HDACs, including calcium/calmodulin dependent protein kinase ( CaMK ), protein kinase D (PKD) and G protein coupled receptor kinase ( GRK )
Haga et al., Biochemistry 1997 : These results indicate that Ca2+-calmodulin does not directly interact with the catalytic site of GRK2 but inhibits the kinase activity of GRK2 by interfering with the activation of GRK2 by agonist bound m2 receptors and G protein betagamma subunits