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CANX — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Perry et al., J Biol Chem 2000
:
Overexpression of p76 ( MDM2 ) antagonizes the ability of
p90 ( MDM2 ) to
stimulate the degradation of
p53 and leads to an increase in the levels and activity of p53
Mendrysa et al., Mol Cell Biol 2003
(Body Weight) :
However, the level of p53 protein was not coordinately increased, suggesting that
p90MDM2 can
inhibit the transcriptional activation and apoptotic functions of
p53 in a manner independent of degradation