Gene interactions and pathways from curated databases and text-mining

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CASP12 — MET

Text-mined interactions from Literome

Tulasne et al., Mol Cell Biol 2004 : We report that stress stimuli induce the caspase mediated cleavage of MET in physiological cellular targets, such as epithelial cells, embryonic hepatocytes, and cortical neurons
Huelsenbeck et al., Infect Immun 2007 : The cytotoxic effect of TcdB was executed by caspase-3, as it was responsive to inhibition by acetyl-Asp-Met-Gln-Asp-aldehyde ( Ac-DMQD-CHO ), an inhibitor of caspase-3
Foveau et al., Cell Death Differ 2007 : Nonetheless, stress stimuli can lead to a caspase dependent cleavage of MET within its juxtamembrane region, which generate a proapoptotic 40 kDa fragment (p40 MET)
McCleese et al., Int J Cancer 2009 (Bone Neoplasms...) : Finally, STA-1474 induced tumor regression, caspase-3 activation and downregulation of p-Met/Met and p-Akt/Akt in OSA xenografts
Barbonetti et al., Endocrinology 2010 : The effect of Met-AEA did not involve activation of caspase-9 or caspase-3 and was reverted by washing