Gene interactions and pathways from curated databases and text-mining

◀ Back to RAF1

CASP6 — RAF1

Text-mined interactions from Literome

Terada et al., Biochem Biophys Res Commun 2000 : Conditional activation of c-Raf-1 also suppressed caspase-3 activation and subsequent cell death without affecting Akt activity, providing further evidence for a PI3-K/Akt independent mechanism
Jesenberger et al., J Exp Med 2001 : Raf-1 degradation is SipB- and caspase-1 dependent , and is prevented by proteasome inhibitors
Cornelis et al., Oncogene 2005 (Fibrosarcoma) : Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1 ... These results suggest an important role for caspase-9 mediated cleavage of Raf-1 in the negative feedback regulation of hematopoietic cell apoptosis induced by growth factor withdrawal
Tian et al., Int J Oncol 2006 : In our efforts to understand the mechanism by which Raf-1 inhibits caspase activation, we discovered a novel interaction between Raf-1 and XIAP