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CASP16 — CCDC88A

Text-mined interactions from Literome

Vasko et al., DNA repair 2005 : Reduced Ape1 levels also increase caspase-3 activity in the cells, 2-3-fold, 60min after a 1-h exposure to 100 microM H2O2 in the cultures
Unnikrishnan et al., Free Radic Biol Med 2009 : In addition, loss of APE1/Ref-1 increases the apoptotic response to oxidative stress, in which significant increases in GADD45g expression, p53 protein stability, and caspase activity are observed
Cho et al., Mol Cell Neurosci 2010 : Both silencing of APE/Ref-1 by siRNA and inhibition of endonuclease by an antibody significantly increased caspase-3 activity and apoptotic cell death triggered from the early time after exposure to KA
Nho et al., J Ethnopharmacol 2011 : When we measured the affect of APE on intracellular signaling, APE stimulated the apoptotic factors bcl-2, bcl-xl, mcl-1, XIAP, BID, BIK, caspase-3 , caspase-9 and PARP in HepG2 cells
Kim et al., Acta Histochem 2012 (Diabetes Mellitus, Experimental...) : The augmented APE , in association with increased p53, suppressed cleaved caspase-3