◀ Back to RHOA

CCK — RHOA

Text-mined interactions from Literome

Kusama et al., Biochem Biophys Res Commun 2003 (Acute Disease...) : In isolated rat pancreatic acini, protein expression of RhoA and Rho associated kinase, ROCK-II, and the formation of immunocomplex of RhoA with ROCK-II were enhanced by CCK-8 , carbachol, and the phorbol ester TPA
Murthy et al., Am J Physiol Cell Physiol 2004 : Unlike G ( i/o ) -coupled receptor agonists, CCK-8 activated RhoA and stimulated RhoA : PLC-delta1 association
Sabbatini et al., Am J Physiol Cell Physiol 2010 : CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini ... Cholecystokinin (CCK) has been shown to activate RhoA and Rac1, as well as reorganize the actin cytoskeleton and, thereby, modify acinar morphology and amylase secretion in mouse pancreatic acini ... Galpha ( i ) was not required for CCK induced RhoA or Rac1 activation ... The regulator of G protein signaling (RGS) domain of p115-Rho guanine nucleotide exchange factor ( p115-RGS ), a specific inhibitor of Galpha(12/13) mediated signaling, abolished CCK stimulated RhoA activation
Iwata et al., Biochem Biophys Res Commun 2011 : In isolated rat pancreatic acinar cells, CCK stimulation enhanced protein expression and association of RhoA , G ( a13 ), Vav-2, catenin p120 and E-cadherin ... CCK induced translocation and activation of RhoA and actin-filamentous assembly and disassembly
Sabbatini et al., PloS one 2013 : We found that both Ga13 and PKC, independently, regulate CCK induced RhoA translocation and that the PKC isoform involved is PKCa ... Inactive Rac1 influences CCK induced RhoA activation by preventing RhoGDI1 from binding RhoA