Gene interactions and pathways from curated databases and text-mining

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CCL2 — SOD1

Text-mined interactions from Literome

Chen et al., Am J Physiol Heart Circ Physiol 2004 : Adenovirus mediated expression of superoxide dismutase and catalase inhibited TNF-alpha induced MCP-1 gene expression, suggesting important roles of superoxide ( O ( 2 ) ( - ). ) and H ( 2 ) O ( 2 ) in MCP-1 gene activation
Nishi et al., J Cereb Blood Flow Metab 2005 (Ischemic Attack, Transient...) : Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia
Kong et al., Lipids in health and disease 2013 : However, comparing to the model rabbits, levels of TNF-a, IL-1ß and MDA decreased significantly and serum SOD activity increased , gene and protein expressions of E-sel, ICAM-1, VCAM-1 and MCP-1 in aortas decreased significantly with the treatment of kaempferol