Gollmer et al., Blood 2009
:
CCL21 costimulation resulted in increased Ras- and Rac-GTP formation and enhanced phosphorylation of Akt , MEK, and ERK but not p38 or JNK
Xu et al., PloS one 2011
(Carcinoma, Non-Small-Cell Lung...) :
The CCL21/CCR7 interaction significantly enhanced phosphorylation of extracellular signal regulated kinase ( P-ERK ) but not Akt , as measured by Western blot