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CCL3 — IL1B

Text-mined interactions from Literome

Guo et al., J Neurochem 2003 : Interleukin-1beta stimulates macrophage inflammatory protein-1alpha and -1beta expression in human neuronal cells ( NT2-N ) ... We report herein that human neuronal cells ( NT2-N ) produce macrophage inflammatory protein-1alpha and -1beta ( MIP-1alpha and MIP-1beta ), which could be enhanced by interleukin (IL)-1beta at both mRNA and protein levels ... Investigation of the mechanism ( s ) responsible for IL-1beta induced MIP-1alpha and -1beta expression demonstrated that IL-1beta activated nuclear factor kappa B (NF-kappaB) promoter directed luciferase activity in NT2-N cells ... Caffeic acid phenethyl ester, a potent and specific inhibitor of activation of NF-kappaB, not only blocked IL-1beta induced activation of the NF-kappaB promoter but also decreased IL-1beta induced MIP-1alpha and -1beta expression in NT2-N cells ... These data suggest that NF-kappaB is at least partially involved in the IL-1beta mediated action on MIP-1alpha and -1beta in NT2-N cells
Lu et al., Am J Pathol 2003 (Carcinoma, Hepatocellular...) : Four hepatoma cell lines produced CCL3 only in response to interleukin (IL)-1 alpha and IL-1 beta
Oltmanns et al., Exp Lung Res 2003 (Pneumonia...) : Stimulation with TNF-alpha or IL-1beta increased the MIP-1alpha and GM-CSF release from AM of normal controls and patients with pneumonia and interstitial lung disease : however, no further enhancement of MIP-1alpha and GM-CSF production was observed in AM from sarcoidosis patients
Furuichi et al., Crit Care Med 2006 (Kidney Tubular Necrosis, Acute...) : Likewise, in vitro study revealed that stimulation of tubular epithelial cells by IL-1beta and/or H2O2 sequentially induced KC, MIP-1alpha , and MCP-1 in both protein and messenger RNA levels, which is consistent with in vivo results
Fan et al., Immunology 2007 : LPS induced production of tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), IL-10 and interferon-gamma-inducible protein-10 (IP-10); SA induced TNF-alpha, and IL-1beta production ; and GBS induced TNF-alpha, IL-6, IL-1beta, macrophage inflammatory protein-1alpha ( MIP-1alpha ) and keratinocyte chemoattract ( KC ) production were all decreased ( P < 0.05 ) in Galpha ( i2 ) ( -/- ) or Galpha ( i1/3 ) ( -/- ) mice compared with WT mice
Ryu et al., J Periodontol 2007 (Gingivitis...) : MIP-1alpha expression in PMNs and gingival epithelial cells was induced by IL-1beta and LPS, but neither induced MIP-1alpha expression in gingival fibroblasts or osteoblastic cells
Sandell et al., Osteoarthritis Cartilage 2008 (Arthritis) : In the presence of IL-1beta , FGF-18 increased expression of ADAMTS-4, aggrecan, BMP-2, COL2A1, CCL3 , CCL4, CCL20, CXCL1, CXCL3, CXCL6, IL-1beta, IL-6, and IL-8 and decreased ADAMTS-5, MMP-13, CCL2, and CCL8
Kiguchi et al., Pain 2010 (Hyperalgesia...) : PSL induced IL-1beta up-regulation was suppressed by anti-MIP-1alpha and siRNA against CCR1 and CCR5
Berkman et al., J Immunol 1995 : Both LPS ( 1 micrograms/ml ) and IL-1 beta ( 10 ng/ml ) induced the expression of MIP-1 alpha mRNA and the release of MIP-1 alpha protein from these cells ... In the presence of an anti-human IL-10 neutralizing Ab, the release of MIP-1 alpha induced by LPS and IL-1 beta was further enhanced in monocytes but unchanged in alveolar macrophages
Murphy et al., J Neurosci Res 1995 : Interleukin-1 beta , tumor necrosis factor alpha, and MIP-1 alpha had no effect on MIP-1 alpha mRNA expression
Berkman et al., Am J Respir Cell Mol Biol 1996 : LPS- and IL-1 beta induced MIP-1 alpha mRNA expression was reduced by 43 +/- 5 % ( P < 0.01 ) and 41 +/- 4 % ( NS )
Imamura et al., Exp Hematol 1996 : Furthermore, LIF+SCF+IL-1 beta induced increased IL-3 and GM-CSF mRNA expression in hematopoietic cells but induced decreased macrophage inflammatory protein 1 alpha ( MIP1 alpha ) mRNA expression as compared with SCF+IL-1 beta +IL-3
McManus et al., J Immunol 1998 : In response to LPS, TNF-alpha, or IL-1 beta , both MIP-1 alpha and MIP-1 beta were induced at the mRNA and protein levels in a dose- and time dependent manner