Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
SRC
→
CCL5
(increases)
Evidence: Treatment of serum starved HeLa-CD4 cells with herbimycin A (the src-kinase inhibitor) and then stimulation with RANTES (10 micro g/ml) for 24 hours inhibited the enhancement of HIV infection caused by RANTES. RANTES induced tyrosine phosphorylation of src kinases. Phosphorylation of Fyn was detected approximately 30 minutes after RANTES addition and increased in intensity for atleast a further 30 minutes. Phosphorylation of Hck was very rapid and the increase was detectable within 1 min, the r...