Gene interactions and pathways from curated databases and text-mining

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CD40LG — CXCL10

Text-mined interactions from Literome

Mach et al., J Clin Invest 1999 (Arteriosclerosis) : In vitro experiments supported these results and showed that IL-1beta, TNF-alpha, and CD40 ligand potentiated IP-10 expression from IFN-gamma stimulated ECs
D'Aversa et al., Am J Pathol 2002 (Encephalitis, Viral...) : In contrast, IFN-gamma- and CD40L induced IP-10 protein production was mediated by the p38 MAPK pathway
D'Aversa et al., J Neurosci Res 2008 (AIDS Dementia Complex...) : CD40-CD40 ligand interactions in human microglia induce CXCL8 ( interleukin-8 ) secretion by a mechanism dependent on activation of ERK1/2 and nuclear translocation of nuclear factor-kappaB (NFkappaB) and activator protein-1 (AP-1)