Gene interactions and pathways from curated databases and text-mining

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CDC25A — MYLIP

Text-mined interactions from Literome

Lee et al., J Clin Invest 2008 (Disease Models, Animal...) : In contrast, suppression of miR15a in NRCs accelerated cell proliferation, increased Cdc25A expression, and promoted cyst growth
Ma et al., Beijing Da Xue Xue Bao 2011 (Ovarian Neoplasms) : Ectopic expression of miR-449b and miR-34c resulted in lowered adhesion activities by 28 % -34 %, and in cell cycle arrests with increased cell number of 15.62 % and 15.71 % in G1 and with decreased cell number of 15.96 % and 16.56 % in S. Cell cycle related proteins CDK6 and CDC25A were down-regulated ... miR-449b and miR-34c resulted in cell cycle arrests and down-regulation of CDK6, CDC25A and CyclinA in high malignant ovarian cancer cell line SKOV3-ipl
Furuta et al., PloS one 2013 (Carcinoma, Hepatocellular...) : Among the candidates, we successfully identified CCNE1, CDC25A , CCND3, CDK4, and BTRC as direct targets for miR-497 and miR-195