Gene interactions and pathways from curated databases and text-mining

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CDH13 — GSK3B

Text-mined interactions from Literome

Demarchi et al., J Biol Chem 2003 : Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability
Joshi et al., FASEB J 2007 : ILK-siRNA abolished T-cad dependent effects on ( Ser-473 ) Akt/ ( Ser-9 ) GSK3beta phosphorylation, active beta-catenin accumulation, and survival
Farina et al., PloS one 2009 (Breast Neoplasms...) : Here we show that cell density and GSK-3beta regulate cadherin-11 levels in cancer cells ... Our data show that GSK3beta regulates cadherin-11 expression in two ways : first a beta-catenin independent regulation of cadherin-11 steady state mRNA levels, and second a beta-catenin dependent effect on cadherin-11 3'UTR stability and protein translation
Joshi et al., FASEB J 2009 : Similarly to overexpression of native T-cad, cells expressing DeltaII, DeltaIII, or DeltaIV displayed elevated levels of p-Akt and p-GSK3beta and increased proliferation rates ( for DeltaII, DeltaIII ) vs. E. DeltaI- and DeltaV transduced cells exhibited reduced levels of p-Akt and p-GSK3beta and retarded growth rates vs. E. Stimulatory effects of native T-cad overexpression on Akt and GSK3beta phosphorylation were dose dependently inhibited by coexpression of DeltaI or DeltaV