Müller et al., Oncogene 2002
(Colonic Neoplasms) :
Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells
Chen et al., BMB Rep 2010
(Carcinoma...) :
The stable expression of Smad4 increased the expression of E-cadherin , reduced the expression of plasminogen activator inhibitor-1 ( PAI-1 ) and slightly down-regulated the expression of VEGF