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CDH5 — FGF13

Text-mined interactions from Literome

Ciruna et al., Dev Cell 2001 : We propose that modulation of cytoplasmic beta-catenin levels, associated with FGF induced downregulation of E-cadherin , provides a molecular link between FGF and Wnt signaling pathways at the streak
Hatanaka et al., PloS one 2012 : In vitro studies demonstrated that the loss of FGF signaling disrupts the VE-cadherin-catenin complex at adherens junctions by increasing tyrosine phosphorylation levels of VE-cadherin ... In vitro studies demonstrated that the loss of FGF signaling disrupts the VE-cadherin-catenin complex at adherens junctions by increasing tyrosine phosphorylation levels of VE-cadherin ... Among protein tyrosine phosphatases (PTPs) known to be involved in the maintenance of the VE-cadherin complex, suppression of FGF signaling reduces SHP2 expression levels and SHP2/VE-cadherin interaction due to accelerated SHP2 protein degradation