Gene interactions and pathways from curated databases and text-mining

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CDKN1A — NEUROD1

Text-mined interactions from Literome

Sasaki et al., Brain Res Mol Brain Res 2000 : In a mutant P19 cell line, RAC65, treatment with ATRA induced neither p27 accumulation nor neuronal differentiation , but p21 mRNA expression increased markedly
Wainwright et al., Proc Natl Acad Sci U S A 2001 (Neuroblastoma) : Accordingly, overexpression of p21 ( Cip1 ) but not p16(INK4A) induces neuronal differentiation of untreated NB cells
Qiu et al., J Cell Biol 1991 : Induction of neuronal differentiation and ornithine decarboxylase ( ODCase ) transcription by oncogenic p21N-ras does not occur in compactin treated cells indicating that activity of oncogenic p21N-ras expressed in PC12 cells is abolished by compactin treatment
Szeberényi et al., Mol Cell Biol 1990 (Adrenal Gland Neoplasms...) : However, lower levels of p21 ( Asn-17 ) expression were sufficient to block neuronal differentiation without inhibiting induction of these early-response genes