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CEBPA — SIRT1

Text-mined interactions from Literome

Skokowa et al., Nat Med 2009 : The molecular events triggered by NAMPT include NAD ( + ) -dependent sirtuin-1 activation, subsequent induction of CCAAT/enhancer binding protein-alpha and CCAAT/enhancer binding protein-beta, and, ultimately, upregulation of G-CSF synthesis and G-CSF receptor expression
Jin et al., Cell Res 2010 : C/EBPalpha regulates SIRT1 expression during adipogenesis ... C/EBPalpha , but not C/EBPalphap30, activated SIRT1 promoter in both HeLa cells and 3T3-L1 preadipocytes ... In preadipocytes, ectopic expression of C/EBPalpha upregulated SIRT1 protein level and knockdown of C/EBPalpha led to the decrease of SIRT1 protein level ... These data demonstrate that C/EBPalpha regulates SIRT1 expression during adipogenesis by directly binding to the SIRT1 promoter