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CES1 — CSF1
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Watanabe et al., Ann N Y Acad Sci 1995
(Arteriosclerosis) :
To elucidate the role of M-CSF in the atherogenic process in vitro and in vivo, we studied the
effects of
M-CSF on enzyme activities of acidic cholesteryl ester ( CE ) hydrolase, neutral CE hydrolase, and acyl-coenzyme
A:cholesterol acyltransferase (ACAT) , and 300 micrograms of M-CSF was intravenously injected into WHHL rabbits aged 2.5 months for 8.5 months
Inaba et al., J Clin Invest 1993
:
M-CSF ( 100 ng/ml )
enhanced acidic and neutral CE hydrolase and
ACAT activities by 3.2-, 4-, and 2.3-fold, respectively, in the presence of acetyl LDL