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CHAT — LIF
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Bartoe et al., J Neurochem 2000
:
SHP-2 also negatively regulates
LIF dependent expression of
choline acetyltransferase , but this regulation could be dissociated from its effects on MAPK activation
Rao et al., Dev Biol 1992
:
Depolarization is known to block cholinergic induction in response to heart cell conditioned medium and we found that it blocked the
induction of
choline acetyltransferase (ChAT) and peptides by recombinant cholinergic differentiation
factor/leukemia inhibitory factor ( CDF/LIF )
Michikawa et al., Neurosci Lett 1992
:
Leukemia inhibitory factor (LIF) mediated increase of
choline acetyltransferase activity in mouse spinal cord neurons in culture ... The
effects of
leukemia inhibitory factor (LIF) on
choline acetyltransferase (ChAT) enzyme activity in cultured mouse spinal cord neurons were examined
Martinou et al., Neuron 1992
:
CDF/LIF also
increased ChAT activity in dorsal spinal cord cultures, but had no detectable effect on ChAT levels in septal or striatal neuronal cultures
Berrard et al., J Neurochem 1995
:
We thus tested the effects on VAChT gene expression of the cholinergic differentiation
factor/leukemia inhibitory factor and retinoic acid, both of which
induce ChAT activity and increase ChAT mRNA levels in cultured sympathetic neurons
Zurn et al., Dev Biol 1994
:
CNTF and
LIF increased
ChAT activity only in the rostral and central VM, which contain cranial motor nuclei, and not in the caudal VM, which contains the rostroventral part of the pedunculopontine nucleus
Cervini et al., Neuroreport 1994
:
By use of the reverse transcription polymerase chain reaction technique we analysed the
effects of
CDF/LIF and RA on the levels of
ChAT , TH and DBH mRNAs
Johnson et al., J Biol Chem 1994
:
In contrast, while
leukemia inhibitory factor induction of
choline acetyltransferase-luciferase expression was protein kinase C-independent, there appears to be both protein kinase C-dependent and -independent pathways for induction of choline acetyltransferase-luciferase by ciliary neurotrophic factor