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CLDN3 — TCF3
Text-mined interactions from Literome
Honda et al., Cancer Biol Ther 2007
(Ovarian Neoplasms) :
Finally, siRNA mediated knockdown of Sp1 led to a significant decrease of CLDN3 expression at both the mRNA and protein levels, demonstrating a crucial
role for this
transcription factor in the regulation of
CLDN3
Satake et al., Pathol Int 2008
(Adenocarcinoma...) :
Cdx2
transcription factor regulates
claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma
Shang et al., Neoplasia (New York, N.Y.) 2012
(Fallopian Tube Neoplasms...) :
Loss of either
CLDN3 or CLDN4
resulted in down-regulation of E-cadherin mRNA and protein, increased inhibitory phosphorylation of glycogen synthase kinase-3ß ( GSK-3ß ), and activation of ß-catenin pathway signaling as evidenced by increases in nuclear ß-catenin, the dephosphorylated form of the protein, and transcriptional activity of
ß-catenin/T-cell factor ( TCF )