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Shulga et al., J Biol Chem 2006
:
Suppression of
ACBP levels by small interfering RNA
inhibited the t-Bid induced activation of mitochondrial
mu-calpain and release of apoptosis inducing factor from the mitochondrial intermembrane space and the cleavage of full-length Bid to t-Bid
Solstad et al., Exp Cell Res 2008
:
Our findings introduce the possibility that reversible phosphorylation of
ACBP regulates its ability to activate
calpain in phosphatase inhibitor induced apoptosis and controls the cellular accessibility of long-chain fatty acid-CoAs for cellular signaling