◀ Back to SGK1
CRK — SGK1
Pathways - manually collected, often from reviews:
-
WikiPathways Insulin Signaling:
GSK3B/AKT2/AKT1/SGK3/SGK1/GSK3A/PDPK1/SGK2
→
STXBP2/CYTH3/KIF5B/EHD2/ARF6/RAB4A/CAP1/STXBP1/CRK/STXBP4/TBC1D4/SH2B2/EHD1/ARHGAP33/STX4/SNAP25/RHOQ/SNAP23/CBLB/STXBP3/CBL/FLOT2/CBLC/MYO1C/RHOJ/SORBS1/ARF1/RAPGEF1/VAMP2/FLOT1/KIF3A
(activation)
Text-mined interactions from Literome
BelAiba et al., Circ Res 2006
(Hypertension, Pulmonary) :
These data show that thrombin potently induces Sgk-1 involving NADPH oxidases, phosphatidylinositol 3-kinase,
p38 mitogen activated protein kinase, and phosphoinositide dependent kinase-1, and that
activation of nuclear factor kappaB by
Sgk-1 mediates TF expression and activity by thrombin
Cheng et al., Circ Res 2010
(Carotid Artery Injuries...) :
The mechanism for the
SGK-1 expression
involved MEK1 but not
p38 or JNK signaling pathway