Profita et al., J Pharmacol Exp Ther 2009
(Pulmonary Disease, Chronic Obstructive) :
IL-1beta increased the ChAT and M ( 3 ), TNF-alpha down-regulated M ( 2 ), and CSE increased ChAT and M ( 3 ) expression while down regulating the expression of M ( 2 ) in HFL-1 cells
Kent et al., Int Immunopharmacol 2010
(Pulmonary Disease, Chronic Obstructive) :
qPCR also showed that IL-1beta , GM-CSF and IL-6 mRNA levels were significantly reduced by CSE and further suppressed by dexamethasone