Gene interactions and pathways from curated databases and text-mining

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CTLA4 — HNRNPH1

Text-mined interactions from Literome

Baban et al., Int Immunol 2005 : By ligating CD80/CD86 ( B7 ) molecules, the synthetic immunomodulatory reagent CTLA4-Ig ( soluble synthetic CTLA4 fusion protein ) induces expression of the enzyme indoleamine 2,3-dioxygenase (IDO) in some dendritic cells (DCs) , which acquire potent T cell regulatory functions as a consequence
Zhang et al., Zhonghua Nei Ke Za Zhi 2005 (Lupus Erythematosus, Systemic) : A771726 can inhibit DCs maturation, the immature DCs can inhibit T cells proliferation and refrain T cells from dividing into Th ( 2 ) subtype, and also the immature DCs can induce a sort of regulate T cell ( CD(4) ( + ) CD(25) ( + ) CTLA(4) ( + ) T cell ) production
Ye et al., J Interferon Cytokine Res 2007 : IL-10 treated dendritic cells (DCs) stimulate anergic cytotoxic T lymphocyte associated molecule-4 ( CTLA)-4 expressing CD4 ( + ) T cell responses possibly through downregulation of major histocompetibility complex ( MHC) class II and costimulatory molecule expression on DCs