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CTLA4 — HNRNPH1
Text-mined interactions from Literome
Baban et al., Int Immunol 2005
:
By ligating CD80/CD86 ( B7 ) molecules, the synthetic immunomodulatory reagent
CTLA4-Ig ( soluble synthetic CTLA4 fusion protein )
induces expression of the enzyme indoleamine 2,3-dioxygenase (IDO) in some
dendritic cells (DCs) , which acquire potent T cell regulatory functions as a consequence
Zhang et al., Zhonghua Nei Ke Za Zhi 2005
(Lupus Erythematosus, Systemic) :
A771726 can inhibit DCs maturation, the immature
DCs can inhibit T cells proliferation and refrain T cells from dividing into Th ( 2 ) subtype, and also the immature DCs can
induce a sort of regulate T cell ( CD(4) ( + ) CD(25) ( +
) CTLA(4) ( + ) T cell ) production
Ye et al., J Interferon Cytokine Res 2007
:
IL-10 treated
dendritic cells (DCs) stimulate anergic cytotoxic T lymphocyte associated molecule-4 (
CTLA)-4 expressing CD4 ( + ) T cell responses possibly through downregulation of major histocompetibility complex ( MHC) class II and costimulatory molecule expression on DCs